Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 10/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551424 | 0.92 | PTGS1 (0.65) | PTGS1PTGS2GFERGAACA12 | |
| SCHEMBL8550834 | 0.90 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1KDREGFR | |
| SCHEMBL8554524 | 0.90 | PTGS1 (0.62) | PTGS1PTGS2GFERCYP3A4CYP2C9 | |
| SCHEMBL8554553 | 0.90 | PTGS2 (0.66) | PTGS1PTGS2GFERGAAL3MBTL1 | |
| SCHEMBL8553948 | 0.89 | PTGS1 (0.62) | PTGS1PTGS2GFER | |
| SCHEMBL8555698 | 0.87 | PTGS1 (0.59) | PTGS1PTGS2GFERALDH1A1CA12 | |
| SCHEMBL8556342 | 0.84 | PTGS2 (0.72) | PTGS1PTGS2GFERALDH1A1SMN1; SMN2 | |
| SCHEMBL8554179 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2GFERALDH1A1CA12 | |
| SCHEMBL1463910 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2GFER | |
| SCHEMBL8557299 | 0.80 | PTGS1 (0.53) | PTGS1PTGS2ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |