Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551424 | 0.92 | PTGS1 (0.65) | PTGS1PTGS2GFERNPSR1XDH | |
| SCHEMBL8552523 | 0.90 | PTGS2 (0.66) | PTGS1PTGS2GFERLMNAKMT2A | |
| SCHEMBL8552452 | 0.90 | PTGS1 (0.62) | PTGS1PTGS2GFERCYP2C9CYP3A4 | |
| SCHEMBL8554553 | 0.90 | PTGS2 (0.66) | PTGS1PTGS2GFERLMNA | |
| SCHEMBL8553948 | 0.89 | PTGS1 (0.62) | PTGS1PTGS2GFERLMNANPSR1 | |
| SCHEMBL8555698 | 0.87 | PTGS1 (0.59) | PTGS1PTGS2GFERPOLBMEN1 | |
| SCHEMBL8556342 | 0.84 | PTGS2 (0.72) | PTGS1PTGS2GFERLMNAKMT2A | |
| SCHEMBL8554179 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2GFERCNKSR1CA12 | |
| SCHEMBL8555161 | 0.80 | PTGS2 (0.53) | PTGS1PTGS2LMNAKMT2ACA12 | |
| SCHEMBL8550834 | 0.80 | PTGS2 (0.66) | PTGS1PTGS2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |