Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | CNKSR1 | Q969H4 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554524 | 0.92 | PTGS1 (0.62) | PTGS1PTGS2GFERCNKSR1CA12 | |
| SCHEMBL8552452 | 0.92 | PTGS1 (0.62) | PTGS1PTGS2GFERCA12CA1 | |
| SCHEMBL8554553 | 0.92 | PTGS2 (0.66) | PTGS1PTGS2GFERFPR1GAA | |
| SCHEMBL8553948 | 0.90 | PTGS1 (0.62) | PTGS1PTGS2GFERFPR1CNKSR1 | |
| SCHEMBL8555698 | 0.90 | PTGS1 (0.59) | PTGS1PTGS2GFERCA12CA1 | |
| SCHEMBL8556342 | 0.86 | PTGS2 (0.72) | PTGS1PTGS2GFERFPR1 | |
| SCHEMBL8554179 | 0.86 | PTGS1 (0.54) | PTGS1PTGS2GFERFPR1CNKSR1 | |
| SCHEMBL8552523 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2GFERFPR1CA12 | |
| SCHEMBL8553129 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2GFERFPR1 | |
| SCHEMBL8550834 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |