Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559075 | 0.90 | PTGS2 (0.63) | PTGS1PTGS2ALDH1A1MMP1MMP2 | |
| SCHEMBL8551424 | 0.90 | PTGS1 (0.65) | PTGS1PTGS2GFERCA2CA9 | |
| SCHEMBL8552452 | 0.87 | PTGS1 (0.62) | PTGS1PTGS2ALDH1A1GFERMEN1 | |
| SCHEMBL8554553 | 0.87 | PTGS2 (0.66) | PTGS1PTGS2GFER | |
| SCHEMBL8554524 | 0.87 | PTGS1 (0.62) | PTGS1PTGS2GFERMEN1KMT2A | |
| SCHEMBL8553948 | 0.84 | PTGS1 (0.62) | PTGS1PTGS2GFERMAPT | |
| SCHEMBL8556342 | 0.81 | PTGS2 (0.72) | PTGS1PTGS2ALDH1A1GFERKMT2A | |
| SCHEMBL8551389 | 0.79 | PTGS1 (0.51) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL8554179 | 0.79 | PTGS1 (0.54) | PTGS1PTGS2ALDH1A1GFERCA2 | |
| SCHEMBL8550834 | 0.77 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |