Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140543 | 0.87 | TP53 (0.47) | P2RX7TSHRKMT2APOLBDRD2 | |
| SCHEMBL9147970 | 0.76 | TSHR (0.58) | TSHRKMT2AHDAC1HDAC6 | |
| SCHEMBL7473233 | 0.73 | SIRT1 (0.49) | CYP2A13P2RX7SIGMAR1MAPTKDM4E | |
| SCHEMBL8554596 | 0.71 | HDAC1 (0.53) | TSHRKMT2APOLBLMNADRD2 | |
| SCHEMBL2208731 | 0.71 | HDAC1 (0.53) | TSHRMAPTKMT2APOLBDRD2 | |
| SCHEMBL28238549 | 0.71 | HDAC1 (0.56) | TSHRKMT2APOLBDRD2DRD4 | |
| SCHEMBL23882024 | 0.70 | TUBB4A (0.52) | TSHRMAPTKMT2AMEN1LMNA | |
| SCHEMBL1555164 | 0.70 | KMT2A (0.55) | TSHRMAPTKMT2APOLBLMNA | |
| SCHEMBL5442628 | 0.69 | TSHR (0.53) | TSHRMAPTKMT2APOLBDRD2 | |
| SCHEMBL12388072 | 0.69 | LMNA (0.52) | TSHRKMT2ALMNASMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |