Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553140 | 0.91 | MAPT (0.39) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8837860 | 0.87 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8308344 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8305023 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8307605 | 0.77 | MAPK1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8308345 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8305025 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8837925 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL27445439 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL16547892 | 0.73 | MAPT (0.57) | ALDH1A1KDM4EHPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685474-B1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1998-09-16 | — | — | EP | disclosed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |