Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 12/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552868 | 0.93 | DGAT2 (0.42) | DGAT2NPY1RHRH3CHRNB2CHRNB4 | |
| SCHEMBL8556171 | 0.92 | NPY1R (0.45) | DGAT2NPY1R | |
| SCHEMBL8551239 | 0.90 | DGAT2 (0.38) | DGAT2NPY1RHRH3CHRNB2CHRNB4 | |
| SCHEMBL8552384 | 0.89 | NPY1R (0.39) | DGAT2NPY1RHRH3CHRNB2CHRNB4 | |
| SCHEMBL8551499 | 0.86 | DGAT2 (0.37) | DGAT2NPY1RHRH3CHRNB2CHRNB4 | |
| SCHEMBL8557639 | 0.86 | L3MBTL1 (0.38) | DGAT2NPY1RCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8553401 | 0.82 | RAB9A (0.41) | DGAT2 | |
| SCHEMBL8554479 | 0.82 | NPY1R (0.45) | DGAT2NPY1R | |
| SCHEMBL8554095 | 0.81 | NPY1R (0.58) | NPY1R | |
| SCHEMBL8552606 | 0.80 | DGAT2 (0.43) | DGAT2NPY1RHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |