Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8551349 | 0.99 | SMYD3 (0.41) | SMYD3ITGB3ITGA2BCPB1F2R | |
| Hydrochloric Acid SCHEMBL8657208 | 0.88 | SMYD3 (0.41) | SMYD3ITGB3ITGA2BCPB1 | |
| Hydrochloric Acid SCHEMBL8591588 | 0.88 | SMYD3 (0.41) | SMYD3ITGB3ITGA2BCPB1 | |
| SCHEMBL8554518 | 0.74 | L3MBTL1 (0.47) | — | |
| SCHEMBL13406413 | 0.73 | KDM2B (0.49) | CPB1KDM2B | |
| SCHEMBL8550484 | 0.72 | SMYD3 (0.41) | SMYD3ITGB3ITGA2B | |
| SCHEMBL8550491 | 0.72 | SMYD3 (0.41) | SMYD3ITGB3ITGA2B | |
| SCHEMBL8549822 | 0.70 | ITGB3 (0.42) | SMYD3ITGB3ITGA2B | |
| SCHEMBL8549817 | 0.70 | ITGB3 (0.42) | SMYD3ITGB3ITGA2B | |
| SCHEMBL9409598 | 0.70 | DGAT1 (0.47) | SMYD3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | claimed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | claimed |