Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118689 | 0.88 | KCNA5 (0.48) | SMN1; SMN2NPC1TP53RAB9AMAPT | |
| SCHEMBL8550969 | 0.87 | EPHX1 (0.46) | EPHX1SMN1; SMN2ADRB3ADRB1RXRA | |
| SCHEMBL8555638 | 0.87 | SUCNR1 (0.43) | ADRB3ADRB1LMNAGAAPTAFR | |
| SCHEMBL8551743 | 0.85 | KMO (0.51) | ADRB3ADRB1LMNAGAARXRA | |
| SCHEMBL8552914 | 0.84 | CYP17A1 (0.48) | PKMLMNA | |
| SCHEMBL8552459 | 0.84 | CYP17A1 (0.44) | ADRB3ADRB1PTAFRFFAR1 | |
| SCHEMBL8552624 | 0.84 | CYP19A1 (0.47) | SMN1; SMN2ADRB3ADRB1MKNK1MKNK2 | |
| SCHEMBL8109544 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMADRB3ADRB1GAA | |
| SCHEMBL8118264 | 0.83 | DGAT2 (0.39) | ADRB3ADRB1DGAT2KCNA5FFAR1 | |
| SCHEMBL8118468 | 0.83 | KCNA5 (0.45) | ADRB3ADRB1KCNA5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |