Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624433 | 0.87 | SLC5A1 (0.51) | L3MBTL1TSHRSLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL27376595 | 0.85 | CASP1 (0.56) | L3MBTL1TSHRSLC5A1SLC5A2KMT2A | |
| SCHEMBL31490076 | 0.85 | SLC5A1 (0.54) | L3MBTL1TSHRSLC5A1SLC5A2KMT2A | |
| SCHEMBL10048208 | 0.81 | SLC5A1 (0.65) | L3MBTL1DRD4SLC5A1SLC5A2KMT2A | |
| SCHEMBL31667554 | 0.81 | L3MBTL1 (0.70) | L3MBTL1TSHRDRD4KMT2AMEN1 | |
| SCHEMBL8554427 | 0.80 | TSHR (0.64) | L3MBTL1TSHRDRD4SIRT2SIRT1 | |
| SCHEMBL9309020 | 0.79 | POLB (0.69) | DRD4GFERKMT2AMEN1ALDH1A1 | |
| SCHEMBL4506469 | 0.78 | ALDH1A1 (0.69) | L3MBTL1TSHRDRD4KMT2AMEN1 | |
| SCHEMBL8554715 | 0.78 | L3MBTL1 (1.00) | L3MBTL1TSHRDRD4KMT2AMEN1 | |
| SCHEMBL6471926 | 0.78 | PIK3CG (0.48) | L3MBTL1SLC5A1SLC5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |