Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376595 | 0.93 | CASP1 (0.56) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 | |
| SCHEMBL6471926 | 0.90 | PIK3CG (0.48) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 | |
| SCHEMBL27377925 | 0.87 | SLC5A1 (0.48) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 | |
| SCHEMBL8553880 | 0.87 | L3MBTL1 (0.64) | SLC5A1SLC5A2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL30806670 | 0.85 | PIK3CG (0.48) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 | |
| SCHEMBL27378218 | 0.85 | PIK3CG (0.48) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 | |
| SCHEMBL282621 | 0.85 | TERT (0.44) | SLC5A1SLC5A2CASP1CASP3CASP4 | |
| SCHEMBL8130592 | 0.84 | TERT (0.48) | SLC5A1SLC5A2CASP1CASP3CASP4 | |
| SCHEMBL10048208 | 0.84 | SLC5A1 (0.65) | SLC5A1SLC5A2L3MBTL1 | |
| SCHEMBL8557086 | 0.83 | TSHR (0.67) | SLC5A1SLC5A2L3MBTL1CASP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |