Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554310 | 0.91 | TSHR (0.48) | TSHRPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8605054 | 0.84 | TSHR (0.43) | TSHRPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8551698 | 0.84 | ALDH1A1 (0.45) | TSHRPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL7468643 | 0.82 | TSHR (0.42) | TSHRPPARGALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8554111 | 0.81 | TSHR (0.48) | TSHRPPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8595934 | 0.80 | TSHR (0.44) | TSHRPPARGALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8557746 | 0.80 | TSHR (0.45) | TSHRPPARGALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8551630 | 0.80 | TSHR (0.43) | TSHRPPARGALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8602443 | 0.79 | HTT (0.51) | TSHRPPARGALDH1A1 | |
| SCHEMBL8554476 | 0.79 | TSHR (0.46) | TSHRPPARGALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |