Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | EDNRB | P24530 | 4/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560355 | 0.92 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8560073 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8558287 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8557580 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8556381 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8557399 | 0.84 | MAPT (0.49) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8558680 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8559268 | 0.84 | MAPT (0.42) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8558062 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAEDNRAEDNRB | |
| SCHEMBL8559259 | 0.83 | MAPT (0.47) | ALDH1A1MAPTLMNAEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |