Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.42 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554061 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8557580 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8557399 | 0.89 | MAPT (0.49) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8556381 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8557926 | 0.86 | LMNA (0.49) | ALDH1A1MAPTLMNAPGRTSHR | |
| SCHEMBL8559666 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8560355 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAGAATSHR | |
| SCHEMBL8556764 | 0.85 | MAPT (0.54) | ALDH1A1MAPTLMNAGAATSHR | |
| SCHEMBL8555221 | 0.85 | MAPT (0.56) | ALDH1A1MAPTLMNAPGRGAA | |
| SCHEMBL8555983 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAPGRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |