Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680365 | 0.75 | PBRM1 (0.35) | ATMALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL9680412 | 0.75 | KMT2A (0.34) | ATMALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9682041 | 0.75 | KDM4E (0.42) | ATMALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4260102 | 0.73 | ATM (0.45) | ATML3MBTL1POLBHTR2CHTR2B | |
| SCHEMBL9682834 | 0.73 | PDPK1 (0.39) | — | |
| SCHEMBL9680947 | 0.70 | PDPK1 (0.43) | L3MBTL1POLBCA12CA9SMN1; SMN2 | |
| SCHEMBL7826302 | 0.69 | HIF1A (0.60) | ATML3MBTL1HTR2CHTR2BCA12 | |
| SCHEMBL9680374 | 0.68 | ALDH1A1 (0.42) | L3MBTL1POLBCA12CA9ALDH1A1 | |
| SCHEMBL9132454 | 0.67 | IGF1R (0.46) | — | |
| SCHEMBL20302942 | 0.67 | CA12 (0.60) | ATML3MBTL1POLBHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | claimed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | claimed |