Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680374 | 0.89 | ALDH1A1 (0.42) | RARARARBRARGL3MBTL1KMT2A | |
| SCHEMBL12365911 | 0.82 | RARA (0.43) | RARARARBRARGALOX5OPRD1 | |
| SCHEMBL12365916 | 0.81 | NPC1 (0.44) | RARARARBRARGALOX5OPRD1 | |
| SCHEMBL2263334 | 0.81 | RARA (0.43) | RARARARBRARGALOX5OPRD1 | |
| SCHEMBL9680331 | 0.80 | RARA (0.40) | RARARARBRARGALOX5OPRD1 | |
| SCHEMBL12365140 | 0.79 | RARA (0.55) | RARARARBRARGALOX5OPRD1 | |
| SCHEMBL9682041 | 0.79 | KDM4E (0.42) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9680365 | 0.79 | PBRM1 (0.35) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9680412 | 0.79 | KMT2A (0.34) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL12366037 | 0.79 | RARB (0.43) | RARARARBRARGALOX5OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |