Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680365 | 0.82 | PBRM1 (0.35) | MALT1 | |
| SCHEMBL9682041 | 0.82 | KDM4E (0.42) | DAO | |
| SCHEMBL9680412 | 0.82 | KMT2A (0.34) | MALT1 | |
| SCHEMBL9596467 | 0.81 | ALDH1A1 (0.36) | ABCB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9682845 | 0.79 | PDGFRB (0.41) | DAOMALT1 | |
| SCHEMBL9682813 | 0.78 | PDE4A (0.37) | ABCB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9779797 | 0.78 | PDPK1 (0.38) | PDPK1ABCB1MCL1DAOABCC9 | |
| SCHEMBL9525977 | 0.78 | OPRD1 (0.37) | ABCB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9603010 | 0.77 | PDE4A (0.34) | ABCB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9680947 | 0.76 | PDPK1 (0.43) | PDPK1MCL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |