Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680947 | 0.89 | PDPK1 (0.43) | MAPTRARARARBRARGCA12 | |
| SCHEMBL9682041 | 0.77 | KDM4E (0.42) | ALDH1A1RARARARBRARGKDM4E | |
| SCHEMBL9680412 | 0.77 | KMT2A (0.34) | ALDH1A1MAPTRARARARBRARG | |
| SCHEMBL9680365 | 0.77 | PBRM1 (0.35) | ALDH1A1RARARARBRARGKDM4E | |
| SCHEMBL9682059 | 0.76 | MAPT (0.45) | ALDH1A1MAPTRECQLGLARARA | |
| SCHEMBL9682834 | 0.74 | PDPK1 (0.39) | — | |
| SCHEMBL7277024 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTRECQLGLAUSP2 | |
| SCHEMBL9680959 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTRECQLUSP2ALOX15 | |
| SCHEMBL6589881 | 0.71 | RARA (0.45) | ALDH1A1MAPTGLARARARARB | |
| SCHEMBL12365911 | 0.70 | RARA (0.43) | ALDH1A1MAPTRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112839-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-12 | — | — | US | disclosed |