Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974907 | 0.74 | ADRA2C (0.43) | FLT1KDRCYP11B1CYP11B2LTA4H | |
| SCHEMBL2232473 | 0.73 | MET (0.50) | CYP11B1CYP11B2PAX8HSP90AA1 | |
| Ammonia Solution, Strong SCHEMBL28590384 | 0.72 | MET (0.49) | CYP11B1CYP11B2PAX8HSP90AA1 | |
| SCHEMBL30022256 | 0.72 | MET (0.49) | CYP11B1CYP11B2PAX8HSP90AA1 | |
| SCHEMBL8698792 | 0.71 | KDM4E (0.57) | CYP11B1CYP11B2PAX8ABCB1 | |
| SCHEMBL4800049 | 0.69 | HTR2A (0.44) | LTA4HPAX8LOXL2HSP90AA1 | |
| SCHEMBL8532742 | 0.69 | KEAP1 (0.53) | PAX8HSP90AA1 | |
| SCHEMBL5110066 | 0.69 | PAX8 (0.49) | PAX8HSP90AA1 | |
| SCHEMBL28023498 | 0.69 | HSP90AA1 (0.46) | PAX8HSP90AA1 | |
| SCHEMBL38230 | 0.69 | MET (0.40) | PAX8ABCB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |