Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232473 | 0.86 | MET (0.50) | PAX8METKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL5102757 | 0.85 | ALDH1A1 (0.50) | PAX8METKDM4EL3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28590384 | 0.85 | MET (0.49) | PAX8METKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL30022256 | 0.85 | MET (0.49) | PAX8METKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL4800049 | 0.81 | HTR2A (0.44) | PAX8METKDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL28023498 | 0.81 | HSP90AA1 (0.46) | PAX8METKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL29593270 | 0.80 | L3MBTL1 (0.61) | KDM4EL3MBTL1ALDH1A1KMT2ATSHR | |
| SCHEMBL360470 | 0.80 | L3MBTL1 (0.61) | KDM4EL3MBTL1ALDH1A1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL28880679 | 0.80 | KDM4E (0.54) | PAX8METKDM4EHSP90AA1TSHR | |
| SCHEMBL6310826 | 0.78 | TBXAS1 (0.50) | KDM4EALDH1A1HSP90AA1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715425-B | Herbicidal quinolines | 先正达参股股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3191465-B1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-19 | — | — | EP | disclosed |
| US-9980486-B2 | Herbicidal quinolines | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |
| US-7342116-B2 | Process for producing heterocyclic aldehyde | KOEI CHEMICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-20050124807-A1 | oxidation of a hetero alcohol in presence od an 2,2,6,6-teraalkylpiperidin-1-oxy comound | KOEI CHEMICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| US-4753947-A | Certain fungicidal alphabenzyl-3-pyridylmethanol, the corresponding chloro derivatives thereof or the N-oxides thereof | HOFFMANN-LA ROCHE INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4678790-A | AGRICULTURE HORTICULTURE | HOFFMAN-LA ROCHE INC. (US) | 1987-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124807-A1 | oxidation of a hetero alcohol in presence od an 2,2,6,6-teraalkylpiperidin-1-oxy comound | ADH1C, ADH1A, AOX1 | PAX8 4426/4885MET 1470/4885KDM4E 3250/4885 |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | NQO2, DDT, ATP1B1 | PAX8 2493/4885MET 4291/4885KDM4E 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.