SCHEMBL8554415

SCHEMBL8554415

CCc1nc(NC)sc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.42
CCNA2 P20248 2/20 0.42
CDK2 P24941 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
RAB9A P51151 3/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 3/20 0.38
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
NPC1 O15118 3/20 0.36
LDHA P00338 1/20 0.35
JAK2 O60674 3/20 0.35
EGFR P00533 3/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8552123 0.84 CCNA2 (0.48) CCNA2CDK2L3MBTL1RAB9ATSHR
SCHEMBL7144220 0.79 MEN1 (0.40) CCNA2CDK2RAB9ASMN1; SMN2MEN1
SCHEMBL8551869 0.78 CCNA2 (0.49) CCNA2CDK2RAB9ASMN1; SMN2KMT2A
SCHEMBL9368491 0.76 L3MBTL1 (0.42) L3MBTL1RAB9ATSHRSMN1; SMN2MEN1
SCHEMBL1444863 0.76 GPR35 (0.38) L3MBTL1RAB9ATSHRSMN1; SMN2MEN1
SCHEMBL8554963 0.76 ALDH1A1 (0.55) GFERCCNA2CDK2L3MBTL1RAB9A
SCHEMBL7691178 0.76 LCK (0.47) TSHRMEN1KMT2AALDH1A1
SCHEMBL9642917 0.76 RAB9A (0.40) L3MBTL1RAB9ATSHRSMN1; SMN2MEN1
SCHEMBL9643435 0.74 ALDH1A1 (0.36) L3MBTL1RAB9ATSHRSMN1; SMN2MEN1
SCHEMBL1539908 0.74 ALDH1A1 (0.45) L3MBTL1RAB9ATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639574-B1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD (KR) 1998-06-10 EP disclosed
US-5514643-A FUNGICIDES FOR PLANTS LUCKY LTD. (KR) 1996-05-07 US disclosed
EP-0639574-A1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD. (KR) 1995-02-22 EP disclosed