Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551743 | 0.92 | KMO (0.51) | SUCNR1KMOADRB3ADRB1ADRB2 | |
| SCHEMBL8552914 | 0.87 | CYP17A1 (0.48) | FYNKMT2ALMNA | |
| SCHEMBL8554677 | 0.87 | EPHX1 (0.42) | ADRB3ADRB1KCNA5FFAR1LMNA | |
| SCHEMBL8552459 | 0.85 | CYP17A1 (0.44) | ADRB3ADRB1FFAR1PTAFR | |
| SCHEMBL8552624 | 0.85 | CYP19A1 (0.47) | ADRB3ADRB1KCNA5ALDH1A1 | |
| SCHEMBL8109544 | 0.85 | SMN1; SMN2 (0.44) | ADRB3ADRB1KCNA5HTTKCNH2 | |
| SCHEMBL8118264 | 0.84 | DGAT2 (0.39) | ADRB3ADRB1ADRB2KCNA5KCNH2 | |
| SCHEMBL8118468 | 0.84 | KCNA5 (0.45) | SUCNR1ADRB3ADRB1ADRB2KCNA5 | |
| SCHEMBL8118689 | 0.84 | KCNA5 (0.48) | KCNA5PTAFR | |
| SCHEMBL8123208 | 0.84 | MKNK1 (0.46) | ADRB3ADRB1FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |