Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KAT7 | O95251 | 1/20 | 0.40 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026371 | 0.95 | KMT2A (0.41) | PTGS2PTGS1MAPTSLC40A1PIK3CD | |
| SCHEMBL8559429 | 0.91 | AAK1 (0.45) | MAPTSLC40A1PI4KBALDH1A1KAT7 | |
| SCHEMBL8560184 | 0.89 | MAPT (0.46) | PTGS2PTGS1MAPTSLC40A1PI4KB | |
| SCHEMBL8554941 | 0.88 | MAPT (0.41) | MAPTSLC40A1ALDH1A1TSHRLMNA | |
| SCHEMBL8558562 | 0.87 | MAPT (0.43) | MAPTSLC40A1ALDH1A1KAT7KAT6B | |
| SCHEMBL8555756 | 0.86 | MAPT (0.46) | MAPTSLC40A1PI4KBALDH1A1KAT7 | |
| SCHEMBL8559236 | 0.85 | KMT2A (0.47) | MAPTALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8561410 | 0.85 | PTGS2 (0.47) | PTGS2PTGS1MAPTSLC40A1HTR6 | |
| SCHEMBL8556972 | 0.84 | ALDH1A1 (0.49) | MAPTALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL8559996 | 0.83 | CCNT1 (0.41) | MAPTSLC40A1PIK3CDALDH1A1KAT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |