Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174928 | 0.92 | GNAI3 (0.47) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL8556452 | 0.90 | GNAI3 (0.43) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL852008 | 0.87 | CYP1A2 (0.46) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL29602469 | 0.86 | GNAO1 (0.46) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL8162908 | 0.84 | GNAO1 (0.48) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL27986982 | 0.84 | GNAO1 (0.43) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL28992205 | 0.84 | CYP1A2 (0.55) | DGKAUSP2ALDH1A1EPHX2 | |
| SCHEMBL14173380 | 0.83 | ALDH1A1 (0.51) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL13106126 | 0.82 | ITGB3 (0.39) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL11858248 | 0.82 | DGKA (0.56) | DGKAUSP2ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |