SCHEMBL8555020

SCHEMBL8555020

CC(C)Oc1ccc(C(=O)O)cc1C(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.53
RXRB P28702 2/20 0.53
RXRG P48443 1/20 0.53
KMT2A Q03164 2/20 0.53
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA7 P43166 1/20 0.49
TPMT P51580 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
ACE2 Q9BYF1 2/20 0.47
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
HTT P42858 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21079315 0.87 KMT2A (0.50) RXRARXRBRXRGKMT2ACA12
SCHEMBL17014698 0.87 HTT (0.46) RXRARXRBRXRGKMT2ACA12
SCHEMBL8554478 0.86 ALDH1A1 (0.52) RXRARXRBRXRGKMT2ATSHR
SCHEMBL13066210 0.86 RXRA (0.64) RXRARXRBRXRGKMT2ACA12
SCHEMBL9944064 0.85 PKM (0.54) RXRARXRBRXRGKMT2ATSHR
SCHEMBL4695867 0.84 CA12 (0.65) CA12CA1CA2CA4CA6
SCHEMBL3545163 0.84 KMT2A (0.58) RXRARXRBRXRGKMT2ACA12
SCHEMBL22343539 0.82 RXRA (0.41) RXRARXRBRXRGKMT2ACA12
SCHEMBL9005609 0.81 TTR (0.56) RXRARXRBRXRGKMT2ACA12
SCHEMBL2543398 0.81 KMT2A (0.55) RXRARXRBRXRGKMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767281-B2 Manufacturing and purification technology for high purity Propofol Chodankar Nandkumar Kashinath (IN) 2023-09-26 US disclosed
US-11767281-B2 Manufacturing and purification technology for high purity Propofol Chodankar Nandkumar Kashinath (IN) 2023-09-26 US disclosed
US-20230159420-A1 MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL Chodankar Nandkumar Kashinath (IN) 2023-05-25 US disclosed
US-20230159420-A1 MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL Chodankar Nandkumar Kashinath (IN) 2023-05-25 US disclosed
US-5767146-A Anti-osteopathic composition HOECHST JAPAN LIMITED (JP) 1998-06-16 US disclosed
US-5716995-A TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS HOECHST JAPAN LIMITED (JP) 1998-02-10 US disclosed
US-5703128-A TREATING OSTEOPOROSIS, BONE FRACTURES HOECHST JAPAN LIMITED (JP) 1997-12-30 US disclosed
US-5525618-A ENHANCING OSTEOGENESIS, PREVENTING OSTEOPOROSIS HOECHST JAPAN LIMITED (JP) 1996-06-11 US disclosed
EP-0619116-A2 Use of synthetic retinoids for osteopathy HOECHST JAPAN LIMITED (JP) 1994-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159420-A1 MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL MGMT, SUZ12, U2AF1 RXRA 2243/4885RXRB 2634/4885RXRG 2042/4885
US-11767281-B2 Manufacturing and purification technology for high purity Propofol MGMT, SUZ12, U2AF1 RXRA 2243/4885RXRB 2634/4885RXRG 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.