Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668113 | 0.94 | FPR2 (0.41) | FPR2HDAC6MCHR1MAPTHDAC1 | |
| SCHEMBL8300699 | 0.80 | FPR2 (0.42) | FPR2HDAC6MCHR1MAPTHDAC1 | |
| SCHEMBL8604544 | 0.78 | HDAC6 (0.42) | FPR2HDAC6MCHR1 | |
| SCHEMBL31347254 | 0.74 | MCHR1 (0.46) | FPR2HDAC6MCHR1HDAC1HDAC8 | |
| SCHEMBL8606629 | 0.72 | MCHR1 (0.41) | FPR2HDAC6MCHR1HDAC1HDAC8 | |
| SCHEMBL8555027 | 0.72 | HDAC6 (0.43) | FPR2HDAC6HDAC1HDAC8FPR1 | |
| SCHEMBL8606291 | 0.68 | MCHR1 (0.46) | MCHR1 | |
| SCHEMBL16493351 | 0.66 | FPR2 (0.56) | FPR2HDAC6HDAC1HDAC8FPR1 | |
| SCHEMBL4944455 | 0.66 | HPGD (0.54) | MAPTKCNQ2 | |
| SCHEMBL7812924 | 0.66 | L3MBTL1 (0.52) | FPR2HDAC6HDAC1HDAC8FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670656-A | Process for preparing pyrrolidinones | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |