Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553556 | 0.83 | CYP2C9 (0.70) | CYP2C9CYP2C19KMT2ALMNAPOLB | |
| SCHEMBL8551429 | 0.79 | CYP2C9 (0.56) | CYP2C9CYP2C19CA1CA2CA9 | |
| SCHEMBL3433504 | 0.76 | CYP2C9 (0.55) | CYP2C9CYP2C19NTRK1KMT2ALMNA | |
| SCHEMBL8554179 | 0.76 | PTGS1 (0.54) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL2303216 | 0.75 | LMNA (0.63) | CYP2C9FBP1CA1CA2CA9 | |
| SCHEMBL19732074 | 0.74 | TSHR (0.59) | CYP2C9NTRK1KMT2ATSHRMAPK13 | |
| SCHEMBL8557247 | 0.73 | NTRK1 (0.51) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL8726381 | 0.73 | FBP1 (0.58) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL8415189 | 0.72 | CA1 (0.62) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL8553200 | 0.71 | NTRK1 (0.65) | CYP2C9CYP2C19NTRK1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |