Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 9/20 | 0.56 |
| ▸ | OXTR | P30559 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553556 | 0.88 | CYP2C9 (0.70) | CYP2C9CYP2C19CYP2C18CYP3A4LMNA | |
| SCHEMBL8550596 | 0.81 | NTRK1 (0.65) | LMNAPOLBTSHRNPSR1KMT2A | |
| SCHEMBL8555136 | 0.79 | CYP2C9 (0.50) | CYP2C9CYP2C19CYP2C18CYP3A4LMNA | |
| SCHEMBL23747737 | 0.76 | NAMPT (0.61) | CYP2C9OXTRCYP2C19CYP2C18CYP3A4 | |
| SCHEMBL8552452 | 0.76 | PTGS1 (0.62) | CYP2C9CYP2C19CYP3A4KMT2AFLT1 | |
| SCHEMBL5186566 | 0.75 | LMNA (0.72) | CYP2C9CYP2C19CYP3A4LMNATSHR | |
| SCHEMBL19732074 | 0.74 | TSHR (0.59) | CYP2C9TSHRKMT2AMAPK13MAPK12 | |
| SCHEMBL3433504 | 0.73 | CYP2C9 (0.55) | CYP2C9CYP2C19CYP2C18CYP3A4LMNA | |
| SCHEMBL9529388 | 0.72 | LMNA (0.63) | CYP2C9LMNAKMT2AFLT1FLT4 | |
| SCHEMBL1984012 | 0.72 | NTRK1 (0.48) | LMNAPOLBFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |