Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551429 | 0.88 | CYP2C9 (0.56) | CYP2C9CYP2C19LMNAGAACYP2C18 | |
| SCHEMBL8555136 | 0.83 | CYP2C9 (0.50) | CYP2C9CYP2C19LMNACYP2C18POLB | |
| SCHEMBL8551416 | 0.82 | ALDH1A1 (0.70) | LMNAGAAPOLBTSHRNPSR1 | |
| SCHEMBL8553023 | 0.78 | FPR1 (0.57) | LMNAGAAPOLBNPSR1KMT2A | |
| SCHEMBL15015974 | 0.77 | GRM5 (0.62) | CYP2C9CYP2C19LMNAGAAPOLB | |
| SCHEMBL1013106 | 0.76 | CYP2C9 (0.54) | CYP2C9CYP2C19LMNACYP2C18ALDH1A1 | |
| SCHEMBL3433504 | 0.76 | CYP2C9 (0.55) | CYP2C9CYP2C19LMNAGAACYP2C18 | |
| SCHEMBL8554553 | 0.76 | PTGS2 (0.66) | LMNAGAAL3MBTL1 | |
| SCHEMBL8551669 | 0.76 | HTT (0.68) | LMNAGAAPOLBNPSR1KMT2A | |
| SCHEMBL27885 | 0.75 | LMNA (1.00) | CYP2C9LMNATSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |