Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555339 | 0.94 | TSHR (0.45) | TSHRNPC1RAB9AHPGDKDM4E | |
| SCHEMBL873066 | 0.81 | SIGMAR1 (0.50) | TRPA1 | |
| SCHEMBL16732228 | 0.81 | LMNA (0.41) | TSHRNPC1RAB9AKDM4ELMNA | |
| SCHEMBL8555350 | 0.79 | SLC1A3 (0.41) | TSHRCYP1A2ALDH1A1 | |
| Bicarbonate SCHEMBL28233769 | 0.78 | NPC1 (0.49) | TSHRNPC1RAB9AHPGDKDM4E | |
| Bicarbonate SCHEMBL28036766 | 0.76 | TSHR (0.44) | TSHRNPC1RAB9AKDM4ELMNA | |
| SCHEMBL9417238 | 0.76 | SRR (0.59) | SRR | |
| SCHEMBL2608871 | 0.74 | SIGMAR1 (0.50) | TRPA1 | |
| SCHEMBL31553563 | 0.72 | ALDH1A1 (0.53) | TSHRNPC1RAB9ALMNACYP1A2 | |
| SCHEMBL7701055 | 0.71 | LMNA (0.50) | TSHRNPC1RAB9ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559533-B1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5589592-A | Process for preparing β-lactam derivative and synthetic intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5414081-A | Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent | TANABE SEIYAKU CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0559533-A1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |