Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130792 | 0.83 | JUN (0.37) | HCAR1 | |
| SCHEMBL8127651 | 0.81 | HTR2A (0.31) | — | |
| SCHEMBL7347442 | 0.81 | CES1 (0.38) | HCAR1TGM2CES1 | |
| SCHEMBL8124478 | 0.79 | — | — | |
| SCHEMBL8114995 | 0.79 | — | — | |
| SCHEMBL8557193 | 0.78 | HTR6 (0.35) | TGM2CES1 | |
| SCHEMBL8120881 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL8120381 | 0.76 | — | — | |
| SCHEMBL8555061 | 0.75 | JUN (0.34) | — | |
| SCHEMBL8124575 | 0.75 | ABCC8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647137-A4 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. | UNIV CALIFORNIA WEBER ECKARD (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |