Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557842 | 0.95 | KMT2A (0.43) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL5966775 | 0.76 | CA2 (0.43) | KMT2AMEN1HTTALDH1A1PRSS1 | |
| SCHEMBL8202834 | 0.75 | L3MBTL1 (0.58) | KMT2AHTTKDM4EALDH1A1POLB | |
| [11C]Phenethylguanidine SCHEMBL5461636 | 0.74 | ALDH1A1 (0.64) | KDM4EALDH1A1CA2CA1MMP1 | |
| SCHEMBL8559623 | 0.74 | HDAC1 (0.50) | KMT2AMEN1KDM4EALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL28129395 | 0.74 | L3MBTL1 (0.56) | KMT2AMEN1KDM4EPOLBGAA | |
| SCHEMBL21171920 | 0.74 | TRPV1 (0.56) | KMT2AALDH1A1LMNA | |
| SCHEMBL8799340 | 0.73 | SLC1A3 (0.49) | F2MMP1MMP2MMP9MMP13 | |
| Sulfuric Acid SCHEMBL11558166 | 0.72 | EPHX2 (0.44) | HTTKDM4EALDH1A1CA2CA1 | |
| SCHEMBL8559920 | 0.72 | GAA (0.44) | KMT2AHTTPOLBALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |