Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504591 | 0.81 | KDM4E (0.67) | KDM4EHPGDHSD17B10LMNAMAPT | |
| SCHEMBL15322300 | 0.77 | SPR (0.53) | KDM4EHPGDHSD17B10LMNAMAPT | |
| SCHEMBL2804273 | 0.76 | NR4A2 (0.45) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL2804408 | 0.75 | PLA2G4A (0.46) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8529581 | 0.74 | CPT1A (0.49) | KDM4E | |
| SCHEMBL1495901 | 0.74 | EPHX2 (0.45) | KDM4EHPGDHSD17B10LMNAMAPT | |
| SCHEMBL3352657 | 0.73 | HPGD (0.49) | KDM4EHPGDHSD17B10HDAC3HDAC1 | |
| SCHEMBL913166 | 0.73 | SLC22A12 (0.49) | KDM4EHPGDHDAC1HDAC6ALDH1A1 | |
| SCHEMBL1224223 | 0.72 | TP53 (0.60) | KDM4EHPGDHSD17B10LMNATP53 | |
| SCHEMBL2974692 | 0.72 | HCAR3 (0.53) | HPGDLMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |