Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557995 | 0.85 | KCNJ5 (0.47) | — | |
| SCHEMBL8560730 | 0.85 | POLB (0.53) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL8556932 | 0.85 | AVPR2 (0.48) | KMT2AMEN1MAPT | |
| SCHEMBL8557423 | 0.85 | ACHE (0.51) | RAB9AACHE | |
| SCHEMBL8559361 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9234962 | 0.83 | AVPR1A (0.49) | KMT2AMEN1 | |
| SCHEMBL8559312 | 0.79 | AVPR1A (0.55) | — | |
| SCHEMBL8558825 | 0.79 | AVPR1A (0.53) | KMT2AMEN1 | |
| SCHEMBL8556946 | 0.79 | AVPR2 (0.55) | — | |
| SCHEMBL8555591 | 0.79 | AVPR2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |