Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 13/20 | 0.42 |
| ▸ | DRD3 | P35462 | 12/20 | 0.42 |
| ▸ | DRD2 | P14416 | 11/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553262 | 0.82 | DRD4 (0.42) | DRD4DRD3DRD2NR3C1ACHE | |
| SCHEMBL8555714 | 0.76 | NR3C1 (0.45) | DRD4DRD3DRD2NR3C1ACHE | |
| SCHEMBL8554183 | 0.75 | TSHR (0.58) | DRD4DRD3DRD2ACHETSHR | |
| SCHEMBL9293515 | 0.69 | DRD4 (0.46) | DRD4DRD3DRD2ACHE | |
| SCHEMBL7468310 | 0.69 | ACHE (0.49) | DRD4DRD3DRD2ACHE | |
| SCHEMBL8184218 | 0.63 | ACHE (0.45) | DRD4DRD2ACHE | |
| SCHEMBL20413737 | 0.63 | DRD4 (0.71) | DRD4DRD3DRD2ACHE | |
| SCHEMBL4031211 | 0.63 | DRD4 (0.67) | DRD4DRD3DRD2ACHEPOLB | |
| SCHEMBL9437368 | 0.62 | BACE1 (0.41) | ACHE | |
| SCHEMBL9080065 | 0.62 | ACHE (0.51) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |