Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 12/20 | 0.52 |
| ▸ | DRD3 | P35462 | 11/20 | 0.52 |
| ▸ | DRD2 | P14416 | 10/20 | 0.52 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194597 | 0.78 | TSHR (0.42) | TSHRPOLB | |
| SCHEMBL8553968 | 0.77 | ALOX15 (0.48) | TSHRPOLBHRH3 | |
| SCHEMBL20413737 | 0.77 | DRD4 (0.71) | DRD4DRD3DRD2ACHE | |
| SCHEMBL8555714 | 0.76 | NR3C1 (0.45) | DRD4DRD3DRD2ACHEBCHE | |
| SCHEMBL8553262 | 0.75 | DRD4 (0.42) | DRD4DRD3DRD2ACHEBCHE | |
| SCHEMBL8555717 | 0.75 | DRD4 (0.42) | TSHRDRD4DRD3DRD2ACHE | |
| SCHEMBL31194470 | 0.75 | HPGD (0.46) | TSHRPOLB | |
| SCHEMBL7303767 | 0.74 | TSHR (1.00) | TSHRPOLB | |
| SCHEMBL4498872 | 0.74 | HPGD (0.51) | TSHRPOLB | |
| SCHEMBL3722546 | 0.72 | DRD4 (0.69) | DRD4DRD3DRD2ACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |