Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555714 | 0.83 | NR3C1 (0.45) | DRD4DRD3DRD2NR3C1ACHE | |
| SCHEMBL8555717 | 0.82 | DRD4 (0.42) | DRD4DRD3DRD2NR3C1ACHE | |
| SCHEMBL8554183 | 0.75 | TSHR (0.58) | DRD4DRD3DRD2ACHEBCHE | |
| SCHEMBL803672 | 0.70 | SIGMAR1 (0.59) | DRD2ACHEBCHE | |
| SCHEMBL8556418 | 0.68 | NR3C1 (0.49) | NR3C1ACHEP2RX7SMN1; SMN2 | |
| SCHEMBL2494437 | 0.67 | OPRM1 (0.50) | DRD2ACHEBCHE | |
| SCHEMBL3964744 | 0.67 | MAOB (0.52) | ACHEBCHEKMT2A | |
| SCHEMBL2050353 | 0.67 | MEN1 (0.57) | ACHEBCHEKMT2A | |
| SCHEMBL4512351 | 0.67 | OPRM1 (0.50) | ACHESMN1; SMN2KMT2A | |
| SCHEMBL8052851 | 0.66 | CHRM4 (0.55) | ACHEBCHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |