Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553262 | 0.83 | DRD4 (0.42) | NR3C1KMT2ADRD4DRD3DRD2 | |
| SCHEMBL8557778 | 0.82 | CTSK (0.36) | NR3C1DRD2KCNA3P2RX7 | |
| SCHEMBL8555742 | 0.79 | PLAT (0.36) | NR3C1KCNA3 | |
| SCHEMBL8556418 | 0.78 | NR3C1 (0.49) | NR3C1ACHEP2RX7 | |
| SCHEMBL8554183 | 0.76 | TSHR (0.58) | DRD4DRD3DRD2BCHEACHE | |
| SCHEMBL8555717 | 0.76 | DRD4 (0.42) | NR3C1DRD4DRD3DRD2ACHE | |
| SCHEMBL915402 | 0.71 | KMT2A (0.65) | KMT2AL3MBTL1DRD4DRD3DRD2 | |
| SCHEMBL3635817 | 0.70 | KMT2A (0.56) | KMT2AL3MBTL1DRD4DRD3DRD2 | |
| SCHEMBL30219688 | 0.70 | BCHE (0.58) | KMT2AL3MBTL1DRD4DRD3DRD2 | |
| SCHEMBL3892168 | 0.70 | KMT2A (0.61) | KMT2AL3MBTL1DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |