SCHEMBL8555745

SCHEMBL8555745

Cc1nn(C2CCNCC2)c(N(C=O)OC(C)(C)C)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLAT P00750 1/20 0.36
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8557781 0.88
SCHEMBL8555742 0.70 PLAT (0.36) PLATKDM1A
Tert-Butyl Formate SCHEMBL28782975 0.62 NSD3 (0.35)
SCHEMBL31194597 0.59 TSHR (0.42) PLAT
SCHEMBL29683599 0.58 IGF1R (0.38) PLATKDM1A
SCHEMBL335952 0.57
SCHEMBL1717600 0.57 HPGD (0.49)
SCHEMBL31194470 0.57 HPGD (0.46) PLAT
SCHEMBL29683100 0.56 MEN1 (0.49)
SCHEMBL26621173 0.56 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885890-A1 SULFONYLUREIDOPYRAZOLE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-12-23 EP disclosed