Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557778 | 0.88 | CTSK (0.36) | NR3C1CTSKLPAR1PDE7AKCNA3 | |
| SCHEMBL8555714 | 0.79 | NR3C1 (0.45) | NR3C1KCNA3 | |
| SCHEMBL31082113 | 0.70 | KMT2A (0.34) | CTSKBTK | |
| SCHEMBL31081835 | 0.70 | KMT2A (0.34) | CTSKBTK | |
| SCHEMBL8555745 | 0.70 | PLAT (0.36) | PLATKDM1A | |
| SCHEMBL18300633 | 0.67 | DGAT1 (0.41) | CTSKEGLN2 | |
| SCHEMBL31735465 | 0.65 | PDE7A (0.39) | NR3C1GFERPDE7A | |
| SCHEMBL30867727 | 0.64 | JAK1 (0.43) | GFERLPAR1JAK3 | |
| SCHEMBL31198142 | 0.64 | CTSS (0.34) | CTSKEGLN2 | |
| SCHEMBL31735370 | 0.63 | CHRM2 (0.39) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |