⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557778 | 0.70 | CTSK (0.36) | — | |
| SCHEMBL8553968 | 0.69 | ALOX15 (0.48) | — | |
| SCHEMBL31194597 | 0.58 | TSHR (0.42) | — | |
| SCHEMBL21023808 | 0.57 | ALOX15 (0.45) | — | |
| SCHEMBL1717600 | 0.56 | HPGD (0.49) | — | |
| SCHEMBL31194470 | 0.56 | HPGD (0.46) | — | |
| SCHEMBL16513295 | 0.56 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL4498872 | 0.56 | HPGD (0.51) | — | |
| SCHEMBL16513392 | 0.55 | PKM (0.42) | — | |
| SCHEMBL21357732 | 0.54 | CTSK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |