Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553639 | 0.87 | TDP1 (0.44) | MAPTL3MBTL1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL8967939 | 0.87 | KAT2B (0.50) | MAPTL3MBTL1MAPK1KAT2BRAB9A | |
| Hydrochloric Acid SCHEMBL8968053 | 0.86 | KAT2B (0.51) | MAPTL3MBTL1MAPK1KAT2BRAB9A | |
| SCHEMBL8555066 | 0.85 | CTSB (0.45) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| Maleic Acid SCHEMBL8967637 | 0.79 | NPC1 (0.43) | MAPTL3MBTL1MAPK1KAT2BRAB9A | |
| Fumaric Acid SCHEMBL8968115 | 0.79 | NPC1 (0.43) | MAPTL3MBTL1MAPK1KAT2BRAB9A | |
| SCHEMBL8554926 | 0.78 | HSP90AA1 (0.42) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8554676 | 0.78 | RAB9A (0.40) | MAPTL3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL8554050 | 0.76 | RAB9A (0.42) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8553021 | 0.76 | LMNA (0.52) | MAPTRAB9AALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |