Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | FPR1 | P21462 | 4/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553171 | 0.91 | NTRK1 (0.41) | GAANTRK1CA1CA2CA9 | |
| SCHEMBL8557247 | 0.88 | NTRK1 (0.51) | NTRK1CA1CA2CA9CA12 | |
| SCHEMBL8556018 | 0.86 | LMNA (0.48) | GAANTRK1FPR1KDM4EALDH1A1 | |
| SCHEMBL8554704 | 0.85 | CA1 (0.43) | NTRK1CA1CA2CA9CA12 | |
| SCHEMBL8554369 | 0.84 | GAA (0.46) | GAANTRK1CA1CA2CA9 | |
| SCHEMBL8555845 | 0.78 | LMNA (0.47) | GAANTRK1FPR1KDM4EALDH1A1 | |
| SCHEMBL8555582 | 0.78 | LMNA (0.47) | GAANTRK1FPR1KDM4EALDH1A1 | |
| SCHEMBL8554179 | 0.78 | PTGS1 (0.54) | CA1CA2CA9CA12FPR1 | |
| SCHEMBL8552811 | 0.78 | FPR1 (0.45) | GAANTRK1FPR1KDM4EALDH1A1 | |
| SCHEMBL8552919 | 0.77 | FPR1 (0.44) | GAANTRK1FPR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |