Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557247 | 0.89 | NTRK1 (0.51) | CA1CA2CA9CA12NTRK1 | |
| SCHEMBL8553012 | 0.86 | LMNA (0.49) | MEN1KMT2AKDM4EPOLBFPR1 | |
| SCHEMBL8556060 | 0.85 | GAA (0.47) | CA1CA2CA9CA12NTRK1 | |
| SCHEMBL8553171 | 0.82 | NTRK1 (0.41) | CA1CA2CA9CA12NTRK1 | |
| SCHEMBL8554179 | 0.79 | PTGS1 (0.54) | CA1CA2CA9CA12FBP1 | |
| SCHEMBL8550650 | 0.75 | FPR1 (0.53) | NTRK1KMT2AKDM4EPOLBFPR1 | |
| SCHEMBL8551653 | 0.75 | NTRK1 (0.53) | NTRK1KDM4EPOLBFPR1ALDH1A1 | |
| SCHEMBL1984012 | 0.73 | NTRK1 (0.48) | CA1CA2CA9CA12NTRK1 | |
| SCHEMBL8555862 | 0.73 | NTRK1 (0.48) | CA1CA2CA9CA12NTRK1 | |
| SCHEMBL8552895 | 0.72 | FPR1 (0.48) | NTRK1POLBFPR1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |