Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556018 | 0.91 | LMNA (0.48) | FPR1LMNAALDH1A1GAASLCO1B1 | |
| SCHEMBL8555845 | 0.88 | LMNA (0.47) | FPR1LMNAALDH1A1GAASLCO1B1 | |
| SCHEMBL8555582 | 0.88 | LMNA (0.47) | FPR1LMNAALDH1A1GAASLCO1B1 | |
| SCHEMBL8552919 | 0.88 | FPR1 (0.44) | FPR1LMNAGAASLCO1B1L3MBTL1 | |
| SCHEMBL8553171 | 0.88 | NTRK1 (0.41) | FPR1GAAKDM4ENTRK1 | |
| SCHEMBL8550650 | 0.85 | FPR1 (0.53) | FPR1LMNAALDH1A1GAASLCO1B1 | |
| SCHEMBL8554369 | 0.83 | GAA (0.46) | FPR1LMNAALDH1A1TSHRGAA | |
| SCHEMBL8553012 | 0.82 | LMNA (0.49) | FPR1LMNAALDH1A1CYP2C9GAA | |
| SCHEMBL8556673 | 0.82 | PTGES (0.40) | LMNAALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL8555343 | 0.81 | FPR1 (0.50) | FPR1LMNAALDH1A1GAASLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |