Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556018 | 0.91 | LMNA (0.48) | GAAALDH1A1LMNAFPR1NTRK1 | |
| SCHEMBL8553174 | 0.91 | PTGES (0.43) | ALDH1A1LMNACYP3A4THRBTSHR | |
| SCHEMBL8556673 | 0.90 | PTGES (0.40) | ALDH1A1LMNACYP3A4THRBTSHR | |
| SCHEMBL8557168 | 0.89 | GAA (0.44) | GAAALDH1A1LMNACYP3A4THRB | |
| SCHEMBL8553246 | 0.88 | NTRK1 (0.39) | ALDH1A1LMNACYP3A4THRBTSHR | |
| SCHEMBL1984012 | 0.87 | NTRK1 (0.48) | ALDH1A1LMNASMN1; SMN2PTGESALOX5 | |
| SCHEMBL7355477 | 0.86 | STS (0.40) | ALDH1A1LMNACYP3A4THRBTSHR | |
| SCHEMBL8552075 | 0.86 | FPR1 (0.41) | ALDH1A1LMNACYP3A4THRBTSHR | |
| SCHEMBL8556060 | 0.84 | GAA (0.47) | GAAALDH1A1FPR1MAPK13MAPK12 | |
| SCHEMBL8555582 | 0.83 | LMNA (0.47) | GAAALDH1A1LMNAFPR1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |