Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 12/20 | 0.41 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 6/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552887 | 0.86 | NR4A2 (0.47) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL8555057 | 0.79 | NR4A2 (0.51) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL8557576 | 0.78 | MEN1 (0.52) | RXRARXRBLMNACYP3A4DRD2 | |
| SCHEMBL8554585 | 0.78 | RXRA (0.43) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL8553475 | 0.77 | GAA (0.45) | RXRARXRBKDM4ELMNACYP3A4 | |
| SCHEMBL8552468 | 0.77 | NR4A2 (0.39) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL8558360 | 0.77 | RXRA (0.50) | NR4A2RXRANR4A1NR4A3RXRB | |
| SCHEMBL8557330 | 0.76 | CETP (0.43) | RXRARXRBRXRGKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL8554703 | 0.76 | GAA (0.43) | RXRARXRBKDM4ELMNACYP3A4 | |
| SCHEMBL8554568 | 0.75 | KDR (0.58) | NR4A2RXRANR4A1NR4A3RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |