Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559035 | 0.92 | GRM5 (0.41) | GRM5PPARDFABP4ALOX5PTGS1 | |
| SCHEMBL8553646 | 0.90 | CA12 (0.44) | PPARDFABP4PTGS1RXRARXRB | |
| SCHEMBL8560970 | 0.89 | PTGS1 (0.43) | GRM5PPARDALOX5PTGS1RXRA | |
| SCHEMBL8558002 | 0.89 | CA12 (0.43) | PPARDALOX5PTGS1RXRARXRB | |
| SCHEMBL8559017 | 0.88 | KMT2A (0.46) | PPARDFABP4RXRARXRBRXRG | |
| SCHEMBL8558777 | 0.87 | TDP1 (0.43) | PPARDALOX5PTGS1RXRARXRB | |
| SCHEMBL8553922 | 0.87 | NR4A2 (0.45) | PPARDFABP4RXRARXRBNR4A2 | |
| SCHEMBL7503309 | 0.85 | PTGS1 (0.48) | GRM5PPARDFABP4ALOX5PTGS1 | |
| SCHEMBL7505707 | 0.85 | PTGS1 (0.48) | GRM5PPARDFABP4ALOX5PTGS1 | |
| SCHEMBL8555996 | 0.83 | RXRA (0.43) | PPARDPTGS1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |