Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 9/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558559 | 0.93 | NR4A2 (0.45) | NR4A2PPARDF10PRSS1GPBAR1 | |
| SCHEMBL8556036 | 0.89 | NR4A2 (0.43) | NR4A2PPARDGPBAR1RXRARXRB | |
| SCHEMBL8553646 | 0.88 | CA12 (0.44) | NR4A2PPARDFABP4RXRARXRB | |
| SCHEMBL8556746 | 0.87 | GRM5 (0.41) | NR4A2PPARDFABP4RXRARXRB | |
| SCHEMBL8559017 | 0.87 | KMT2A (0.46) | NR4A2PPARDFABP4RXRARXRB | |
| SCHEMBL7505758 | 0.86 | PPARD (0.49) | NR4A2PPARDGPBAR1CYSLTR1VDR | |
| SCHEMBL7507072 | 0.86 | PPARD (0.49) | NR4A2PPARDGPBAR1CYSLTR1VDR | |
| SCHEMBL8554236 | 0.82 | PPARD (0.42) | NR4A2PPARDGPBAR1RXRARXRB | |
| SCHEMBL8558894 | 0.82 | RXRA (0.46) | NR4A2PPARDVDRFABP4RXRA | |
| SCHEMBL8558002 | 0.81 | CA12 (0.43) | NR4A2PPARDRXRARXRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |