Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 7/20 | 0.44 |
| ▸ | RXRB | P28702 | 7/20 | 0.44 |
| ▸ | RXRG | P48443 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558777 | 0.93 | TDP1 (0.43) | KMT2ATDP1RXRARXRBRXRG | |
| SCHEMBL8555922 | 0.92 | TDP1 (0.46) | KMT2ATDP1RXRARXRBRXRG | |
| SCHEMBL8553646 | 0.90 | CA12 (0.44) | TDP1RXRARXRBRXRGNR4A2 | |
| SCHEMBL8557269 | 0.89 | NR4A2 (0.44) | KMT2ATDP1RXRARXRBRXRG | |
| SCHEMBL8556746 | 0.88 | GRM5 (0.41) | RXRARXRBRXRGNR4A2PPARD | |
| SCHEMBL8553922 | 0.87 | NR4A2 (0.45) | RXRARXRBNR4A2PPARDFABP4 | |
| SCHEMBL7506528 | 0.85 | RXRA (0.47) | KMT2ATDP1RXRARXRBRXRG | |
| SCHEMBL7496715 | 0.85 | RXRA (0.47) | KMT2ATDP1RXRARXRBRXRG | |
| SCHEMBL8560970 | 0.83 | PTGS1 (0.43) | RXRANR4A2TSHRMAPK1PPARD | |
| SCHEMBL8558002 | 0.83 | CA12 (0.43) | RXRARXRBRXRGNR4A2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |